A Mycobacterium tuberculosis komplex archaikus DNS kimutatása humán csontvázmaradványokon
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Tartalom: http://real.mtak.hu/71189/
Archvum: MTA Knyvtr
Gyjtemny: Status = Published

Type = Article
Cm:
A Mycobacterium tuberculosis komplex archaikus DNS kimutatása humán csontvázmaradványokon
Ltrehoz:
Pósa, Annamária
Kiad:
Magyar Biológiai Társaság
Dtum:
2017
Tma:
GN Anthropology / embertan, fizikai antropológia
Tartalmi lers:
Tuberculosis (TB) is one of the oldest diseases and still has
a high prevalence nowadays. The disease is pandemic,
according to the estimation of the WHO 30% of total
population of the world may be infected latently by
Mycobacterium tuberculosis.
Since the 1990s the identification of Mycobacterium
tuberculosis infection has used molecular methods, too.
Paleomicrobial research is also able to identify
mycobacterial DNA from ancient human remains.
In my examination I researched six historical periods for TB
infection, the earliest period is Neolithic, a few samples
from Tápé-Széntéglaégető archaeological site, which is a late
Bronze Age (BC 14th–13rd century) cemetery, Avar Age samples
(Szeged-Kiskundorozsma Kettőshatár II. (Grave No. 263 and
Csárdaszállás-Hanzélytanya) are from the age of the Árpádian
Dynasty. The skeletal material came from the Bácsalmás-Óalmás
archeological site (AD 16th–17th centuries, southern Hungary)
and the remains of Sándor Terézia from the Dominican church
of Vác (AD 18th–19th centuries).
During our research program we successfully adopted long
standing paleomicrobiological techniques on the indigenous
samples, and the TB infection was confirmed in four different
ages. Our studies prove that this disease has accompanied the
human population during its history – for 7000 years at
least. The presence of tuberculosis has been proved in
Hungary since the Neolithic, that is why it would be an
interesting research topic if we could analyse more earlier
periods in the near future. My research has revealed that the
preservation of mycobacterial DNA is much more extensive in
the case of long bones and teeth, than in the case of
vertebrae or ribs. At the same time, data gained indicate the
importance of the selection of the sample, as well as
parallel sampling individually from long bones and teeth.
Nyelv:
angol
Tpus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formtum:
text
Azonost:
Pósa, Annamária (2017) A Mycobacterium tuberculosis komplex archaikus DNS kimutatása humán csontvázmaradványokon. ANTHROPOLOGIAI KÖZLEMÉNYEK, 58. pp. 97-107. ISSN 0003-5440
Kapcsolat:
https://doi.org/10.20330/AnthropKozl.2017.58.97
MTMT:3304521; doi:10.20330/AnthropKozl.2017.58.97