NDA@SZTAKI

Honfoglalók származásának és rokonsági viszonyainak vizsgálata archaeogenetikai módszerekkel

Neparáczki, Endre

Magyar Biológiai Társaság

2017

GN Anthropology / embertan, fizikai antropológia

In the last few decades genetic analysis has been playing an
increasing role in tracing the origin and relation of human
populations. DNA sequences isolated from ancient human
remains can be used, to unravel ancestor-descendant
relationships between populations and reconstruct population
history.
In our research we successfully optimized ancient DNA
extraction methods and adapted the latest haplotyping
methods. We complemented the traditional PCR based HVR
sequencing method with the SNaPshot assay, which is used to
determine 22 haplotype defining SNP-s in the mtDNA coding
region. In the case of bone samples with best DNA
preservation the same method could also be used to determine
the paternal (Y chromosome) haplogroup.
In the last few years the next generation sequencing method
(NGS) has revolutionized the aDNA field, by providing
reliable high quality sequence reads, and enabling to
sequence even whole ancient genomes. Recently we have adapted
the NGS method in our lab (Archoegenetic Laboratory,
University of Szeged) and sequenced whole mtDNA genomes from
a large number of Hungarian conqueror samples. Some 40% of
the conquerors had East-Central Asian origin, other 60% of
the samples had best matches with modern people from Europe.

angol

Article

PeerReviewed

info:eu-repo/semantics/article

text

http://real.mtak.hu/71188/1/Neparaczki_tezis_AK2017.pdf

Neparáczki, Endre (2017) Honfoglalók származásának és rokonsági viszonyainak vizsgálata archaeogenetikai módszerekkel. ANTHROPOLOGIAI KÖZLEMÉNYEK, 58. pp. 91-95. ISSN 0003-5440

http://real.mtak.hu/71188/

https://doi.org/10.20330/AnthropKozl.2017.58.91

MTMT:3304520; doi:10.20330/AnthropKozl.2017.58.91