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Revealing the distribution of transmembrane currents along the dendritic tree of a neuron from extracellular recordings.

  • Metaadatok
Tartalom: http://real.mtak.hu/70836/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published


Type = Article
Cím:
Revealing the distribution of transmembrane currents along the dendritic tree of a neuron from extracellular recordings.
Létrehozó:
Cserpán, Dorottya
Meszéna, Domokos
Wittner, Lucia
TĂłth, Kinga
Ulbert, István
Kiadó:
eLife Sciences Publications
Dátum:
2017
Téma:
QP Physiology / Ă©lettan
RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry / idegkórtan, neurológia, pszichiátria
Tartalmi leírás:
Revealing the current source distribution along the neuronal membrane is a key step on the way to understanding neural computations, however, the experimental and theoretical tools to achieve sufficient spatiotemporal resolution for the estimation remain to be established. Here we address this problem using extracellularly recorded potentials with arbitrarily distributed electrodes for a neuron of known morphology. We use simulations of models with varying complexity to validate the proposed method and to give recommendations for experimental applications. The method is applied to in vitro data from rat hippocampus.
Nyelv:
angol
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Cserpán, Dorottya and Meszéna, Domokos and Wittner, Lucia and Tóth, Kinga and Ulbert, István (2017) Revealing the distribution of transmembrane currents along the dendritic tree of a neuron from extracellular recordings. eLife, 6. e29384. ISSN 2050-084X
Kapcsolat:
https://doi.org/10.7554/eLife.29384
MTMT:3293692; doi:10.7554/eLife.29384