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A propolis extract and the labeling of blood constituents with technetium-99m

  • Metaadatok
Tartalom: http://real.mtak.hu/70079/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published

Type = Article
Cím:
A propolis extract and the labeling of blood constituents with technetium-99m
Létrehozó:
Jesus, L. M.
Abreu, P. R. C.
C. Almeida, Marcela
C. Brito, LavĂ­nia
F. Soares, Sheila
De Souza, D. E.
C. Bernardo, Luciana
Fonseca, A. S.
Bernardo-Filho, M.
Kiadó:
Akadémiai Kiadó
Dátum:
2006
info:eu-repo/date/embargoEnd/2026-06-30
Téma:
QH Natural history / természetrajz
Tartalmi leírás:
Since ancient times propolis has been employed for many human purposes because to their favourable
properties. Blood constituents labeled with technetium-99m (
99m
Tc) have been used in nuclear medicine
procedures. Some authors have reported that synthetic or natural drugs can interfere with the labeling of
blood constituents with
99m
Tc. The aim of this work was to evaluate the action of a propolis extract on
the labeling of blood elements with
99m
Tc. Samples of whole blood of male Wistar rats were incubated
in sequence with an aqueous propolis extract at different concentrations, stannous chloride and
99m
Tc, as
sodium pertechnetate. Blood samples were centrifuged to separate plasma and blood cells, soluble and
insoluble fractions of plasma and blood cells were also separated after precipitation in trichloroacetic
acid solution and centrifugation. The radioactivity was counted and the percentage of incorporated
radioactivity (%ATI) for each fraction was calculated. The data obtained showed that the aqueous propo-
lis extract used decreased significantly the %ATI in plasma proteins at higher concentration studied.
Results suggest that at high concentration the constituents of this extract could alter the labeling of plas-
ma proteins competing with same binding sites of the
99m
Tc on the plasma proteins or acting as antioxi-
dant compounds.
Nyelv:
magyar
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Jesus, L. M. and Abreu, P. R. C. and C. Almeida, Marcela and C. Brito, LavĂ­nia and F. Soares, Sheila and De Souza, D. E. and C. Bernardo, Luciana and Fonseca, A. S. and Bernardo-Filho, M. (2006) A propolis extract and the labeling of blood constituents with technetium-99m. Acta Biologica Hungarica, 57 (2). pp. 191-200. ISSN 0236-5383
Kapcsolat:
https://doi.org/10.1556/ABiol.57.2006.2.6
Létrehozó:
info:eu-repo/semantics/embargoedAccess