Vasopressin and nitric oxide synthesis after three days of water or food deprivation
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Archívum: MTA Könyvtár
Gyűjtemény: Status = Published

Type = Article
Cím:
Vasopressin and nitric oxide synthesis after three days of water or food deprivation
Létrehozó:
Mornagui, B.
Grissa, A.
Duvareille, M.
Gharib, C.
Kamoun, A.
El-Fazaa, S.
Gharbi, N.
Kiadó:
Akadémiai Kiadó
Dátum:
2006
info:eu-repo/date/embargoEnd/2026-03-31
Téma:
QH Natural history / természetrajz
Tartalmi leírás:
Nitric oxide has been suggested to be involved in the regulation of fluid and nutrient homeostasis. In the
present investigation, vasopressin and nitric oxide metabolite (nitrite and nitrate) levels were determined
in plasma of male Wistar rats submitted to water or food deprivation for three days. Hematocrit and
plasma sodium showed marked increase in dehydrated and starved rats. Potassium levels and plasma vol-
ume decreased in both treated groups. Plasma osmolality and vasopressin levels were significantly ele-
vated in water deprived (362.8 ± 7.1 mOsm/kg H
2
O, 17.3 ± 2.7 pg/ml, respectively, p < 0.001) rats, but
not in food deprived (339.9 ± 5.0, 1.34 ± 0.28) rats, compared to the controls (326.1 ± 4.1, 1.47 ± 0.32).
The alterations observed in plasma vasopressin levels were related to plasma osmolality rather than
plasma volume. Plasma levels of nitrite and nitrate were markedly increased in both water and food
deprived rats (respectively, 2.19 ± 0.29 mg/l and 2.22 ± 0.17 mg/l
versus
1.33 ± 0.19 mg/l, both p < 0.01).
There was a significant negative correlation between plasma nitrite and nitrate concentration and plasma
volume. These results suggest that both dehydration and starvation increase plasma nitric oxide, proba-
bly by activation of nitric oxide synthases. The release of nitric oxide may participate in the regulation
of the alteration in blood flow, fluid and nutrient metabolism caused by water deprivation or starvation.
Nyelv:
magyar
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Mornagui, B. and Grissa, A. and Duvareille, M. and Gharib, C. and Kamoun, A. and El-Fazaa, S. and Gharbi, N. (2006) Vasopressin and nitric oxide synthesis after three days of water or food deprivation. Acta Biologica Hungarica, 57 (1). pp. 1-11. ISSN 0236-5383
Kapcsolat:
https://doi.org/10.1556/ABiol.57.2006.1.1
Létrehozó:
info:eu-repo/semantics/embargoedAccess