Acute effect of cigarette smoking on placental circulation — a study by carbon-monoxide measurement and Doppler assessment
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Tartalom: http://real.mtak.hu/66396/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published

Type = Article
Cím:
Acute effect of cigarette smoking on placental circulation — a study by carbon-monoxide measurement and Doppler assessment
Létrehozó:
Óvári, L.
Aranyosi, J.
Balla, Gy.
Kiadó:
AkadĂŠmiai KiadĂł
Dátum:
2009
info:eu-repo/date/embargoEnd/2029-06-30
Téma:
R1 Medicine (General) / orvostudomĂĄny ĂĄltalĂĄban
Tartalmi leírás:
Objective
. Carbon-monoxide (CO) decreases placental vascular impedance. We assessed the consequences of smoking-induced temporary maternal CO-increase on fetal and placental circulation. 
Study design
. In a prospective study twenty-nine smoking pregnant women and their fetuses were evaluated. We determined the changes in maternal blood CO levels after smoking, and the concomitant changes in maternal and fetal circulation. Changes in fetal heart rate, uterine artery (UTA), middle cerebral artery (MCA), and descending aorta (DA) flow were measured by Doppler velocimetry. Changes in maternal CO level and umbilical flow value were assessed by paired t-test. The correlation between CO level and placental flow was assessed by partial correlation test. 
Results
. CO level increased (mean±SD 1.7±0.65% vs. 2.36±0.89, p<0.0001). Nicotine-related maternal circulatory parameters changed significantly, but uterine flow values remained unchanged. Fetal heart rate increased, while flow in MCA and DA showed no change. CO-dependent umbilical artery impedance remained unchanged (Pulsatility Index: 0.956±0.18 vs. 0.948±0.21). Partial correlation between CO level and umbilical arterial impedance showed no significance (r:−0.324). 
Conclusion
. Despite significant CO elevation, the mainly CO-regulated placental flow remained unchanged.
Nyelv:
magyar
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Óvári, L. and Aranyosi, J. and Balla, Gy. (2009) Acute effect of cigarette smoking on placental circulation — a study by carbon-monoxide measurement and Doppler assessment. Acta Physiologica Hungarica, 96 (2). pp. 243-250. ISSN 0231-424X
Kapcsolat:
https://doi.org/10.1556/APhysiol.96.2009.2.9
Létrehozó:
info:eu-repo/semantics/embargoedAccess