Kezdeti tapasztalataink a petefészekszövet-fagyasztás bevezetésével
  • Metaadatok
Tartalom: http://real.mtak.hu/64329/
Archvum: MTA Knyvtr
Gyjtemny: Status = Published


Type = Article
Cm:
Kezdeti tapasztalataink a petefészekszövet-fagyasztás bevezetésével
Ltrehoz:
Fancsovits, Péter
Urbancsek, János
Fónyad, László
Sebestyén, Anna
Csorba, Gézáné
Lehner, Ádám
Kaszás, Zita
Rigó jr., János
Bokor, Attila
Kiad:
Akadémiai Kiadó
Dtum:
2016-12
Tma:
RB Pathology / patológia, kórtan
RG Gynecology and obstetrics / nőgyógyászat, szülészet
Tartalmi lers:
INTRODUCTION:
The oncological treatment may damage ovarian function. To prevent this, it is possible to cryopreserve the ovarian tissue, and to keep the samples for long-term storage. The frozen-thawed tissue could be retransplanted after chemo- or radiotherapy.
AIM:
The aim of our study was to examine the effect of cryopreservation on the viability of ovarian tissue.
METHOD:
We analyzed the survival of frozen-thawed donated ovarian tissues. The quality of the follicles and hormone production in fresh and frozen-thawed samples were compared.
RESULTS:
Histological analysis showed that the number of viable follicles was reduced by 23% in the frozen-thawed samples. However, viable follicles still presented in post thawing ovarian tissues. Maximal estradiol production in frozen-thawed tissues was 908 pg/ml and hormone production was similar to the control tissues. The maximal progesterone production was 1.95 ng/ml post thawing, but these values were lower than the progesterone production of fresh tissues.
CONCLUSIONS:
The method of ovarian cryopreservation used in our laboratory was able preserve the viability of follicles in frozen-thawed ovarian tissues. Orv. Hetil., 2016, 157(49), 1947-1954.
Nyelv:
magyar
Tpus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formtum:
text
Azonost:
Fancsovits, Péter and Urbancsek, János and Fónyad, László and Sebestyén, Anna and Csorba, Gézáné and Lehner, Ádám and Kaszás, Zita and Rigó jr., János and Bokor, Attila (2016) Kezdeti tapasztalataink a petefészekszövet-fagyasztás bevezetésével. Orvosi Hetilap. pp. 1947-1954. ISSN 0030-6002
Kapcsolat:
https://doi.org/10.1556/650.2016.30582
DOI: 10.1556/650.2016.30582