| Tartalom: |
http://real.mtak.hu/63986/ |
| Archívum: |
MTA Könyvtár |
| Gyűjtemény: |
Status = Published
Type = Article
|
| Cím: |
Optimization of the Synthesis of Flavone-Amino Acid and Flavone-Dipeptide Hybrids via Buchwald-Hartwig Reaction
|
| Létrehozó: |
Pajtás, Dávid
KĂłnya, Krisztina
Kiss-Szikszai, Attila
Džubák, Petr
Pethő, Zoltán
Varga, Zoltán
Panyi, György
Patonay, Tamás
|
| Kiadó: |
American Chemical Society
|
| Dátum: |
2017-05-05
|
| Téma: |
QD04 Organic chemistry / szerves kémia
|
| Tartalmi leírás: |
The article describes the development of Buchwald-Hartwig amination of different bromoflavones with amino acid and peptide derivatives as nitrogen source giving unique structures. The previously observed racemization, which occurred during the synthesis of flavone-amino acid hybrids, was successfully prevented in most cases. The biological assays of these novel structures showed cytotoxic effects on different cancer cell lines.
|
| Nyelv: |
angol
|
| Típus: |
Article
PeerReviewed
info:eu-repo/semantics/article
|
| Formátum: |
text
|
| Azonosító: |
Pajtás, Dávid and Kónya, Krisztina and Kiss-Szikszai, Attila and Džubák, Petr and Pethő, Zoltán and Varga, Zoltán and Panyi, György and Patonay, Tamás (2017) Optimization of the Synthesis of Flavone-Amino Acid and Flavone-Dipeptide Hybrids via Buchwald-Hartwig Reaction. JOURNAL OF ORGANIC CHEMISTRY, 82 (9). pp. 4578-4587. ISSN 0022-3263
|
| Kapcsolat: |
https://doi.org/10.1021/acs.joc.7b00124
|
