Differential blood pressure and heart rate responses to supramedullary brain stimulation in cats
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Tartalom: http://real.mtak.hu/63703/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published

Type = Article
Cím:
Differential blood pressure and heart rate responses to supramedullary brain stimulation in cats
Létrehozó:
Ángyån, Z.
Ángyån, L.
Kiadó:
AkadĂŠmiai KiadĂł
Dátum:
2003
info:eu-repo/date/embargoEnd/2023-02-28
Téma:
R1 Medicine (General) / orvostudomĂĄny ĂĄltalĂĄban
Tartalmi leírás:
The purpose of this study was to compare the cardiovascular responses to electrical stimulation of
different supramedullary brain regions. Arterial blood pressure (BP) and heart rate (HR) effects were
elicited by electrical stimulation of the lateral hypothalamus (LH), mammillary bodies (Mm),
substantia nigra (SN), globus pallidus (GP), and the subthalamic nucleus (Sub) in conscious, freely
moving cats. Pressor responses were obtained from all of these regions. The higher intensity of
stimulation the higher increase in BP and HR was obtained. However, clear-cut differences occurred in
the effects both during and after the termination of stimulations. Namely, a continuous increase in BP
and HR was obtained from the LH and SN. In contrast, the initial increase in BP and HR was followed
by a reduction compared to the peak value of the effects of stimulation in the GP and the Sub.
However, the BP and HR never reduced to the pre-stimulation level during the stimulation. Also the
changes following the cessation of stimulation at the different brain loci were dissimilar. The BP and
HR either returned gradually to the pre-stimulation level, or long-lasting oscillation occurred. The
electrical activity of the nucleus of the solitary tract (NTS) and the vagus nerve
co-varied with the
changes in BP and HR. It is concluded that the supramedullary stimulations produce differential
cardiovascular effects, and these effects are modified by the baroreflexes that are activated by the
electrically elicited rise in blood pressure.
Nyelv:
magyar
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Ángyån, Z. and Ángyån, L. (2003) Differential blood pressure and heart rate responses to supramedullary brain stimulation in cats. Acta Physiologica Hungarica, 90 (1). pp. 9-16. ISSN 0231-424X
Kapcsolat:
https://doi.org/10.1556/APhysiol.90.2003.1.2
Létrehozó:
info:eu-repo/semantics/embargoedAccess