NDA
Bejelentkezés
Kapcsolat
The role of the complement system in hereditary angioedema |
Tartalom: | http://real.mtak.hu/63607/ |
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Archívum: | MTA Könyvtár |
Gyűjtemény: |
Status = Published
Type = Article |
Cím: |
The role of the complement system in hereditary angioedema
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Létrehozó: |
Csuka, Dorottya
Veszeli, NĂłra
Varga, Lilian
Prohászka, Zoltán
Farkas, Henriette
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Kiadó: |
Elsevier
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Dátum: |
2017
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Téma: |
RC Internal medicine / belgyógyászat
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Tartalmi leírás: |
Hereditary angioedema (HAE) is a rare, but potentially life-threatening disorder, characterized by acute, recurring, and self-limiting edematous episodes of the face, extremities, trunk, genitals, upper airways, or the gastrointestinal tract. HAE may be caused by the deficiency of C1-inhibitor (C1-INH-HAE) but another type of the disease, hereditary angioedema with normal C1-INH function (nC1-INH-HAE) was also described. The patient population is quite heterogeneous as regards the location, frequency, and severity of edematous attacks, presenting large intra- and inter-individual variation. Here, we review the role of the complement system in the pathomechanism of HAE and also present an overview on the complement parameters having an importance in the diagnosis or in predicting the severity of HAE.
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Nyelv: |
angol
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Típus: |
Article
PeerReviewed
info:eu-repo/semantics/article
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Formátum: |
text
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Azonosító: |
Csuka, Dorottya and Veszeli, Nóra and Varga, Lilian and Prohászka, Zoltán and Farkas, Henriette (2017) The role of the complement system in hereditary angioedema. Molecular Immunology, 89. pp. 59-68. ISSN 0161-5890
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Kapcsolat: |
https://doi.org/10.1016/j.molimm.2017.05.020
MTMT:3238729; doi:10.1016/j.molimm.2017.05.020
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