Unprecedented b-manno type thiodisaccharides with a C-glycosylic function by photoinitiated hydrothiolation of 1-C-substituted glycals (NDA@SZTAKI, Nemzeti Digitális Adattár, National Digital Data Archive)

Unprecedented b-manno type thiodisaccharides with a C-glycosylic function by photoinitiated hydrothiolation of 1-C-substituted glycals

Metaadatok

Tartalom:	http://real.mtak.hu/63473/
Archívum:	MTA Könyvtár
Gyûjtemény:	Status = Published Type = Article
Cím:	Unprecedented b-manno type thiodisaccharides with a C-glycosylic function by photoinitiated hydrothiolation of 1-C-substituted glycals
Létrehozó:	LÃ¡zÃ¡r, LÃ¡szlÃ³ JuhÃ¡sz, LÃ¡szlÃ³ Batta, Gyula BorbÃ¡s, AnikÃ³ SomsÃ¡k, LÃ¡szlÃ³
Kiadó:	Royal Society of Chemistry
Dátum:	2017-01-02
Téma:	QD04 Organic chemistry / szerves kÃ©mia
Tartalmi leírás:	Free-radical hydrothiolation of O-peracylated 1-C-(carbamoyl-, methoxycarbonyl- and cyano) substituted glycals with a range of sugar derived thiols gave the corresponding b-manno type 3-deoxy-3-Sdisaccharides with full regio- and stereoselectivity. The configuration of the glycals (arabino vs. lyxo) and the size of the protecting groups had no significant effect on the outcome of the transformations. Formation of by-products was tracked down by LCMS studies and correlated with the electron density of the double bonds to show that the reactions were synthetically useful with a COOMe and especially with a CONH2 group as the 1-C-substituent.
Nyelv:	magyar
Típus:	Article PeerReviewed info:eu-repo/semantics/article
Formátum:	text
Azonosító:	http://real.mtak.hu/63473/1/C_substituted_glycals_NJC_2017.... LÃ¡zÃ¡r, LÃ¡szlÃ³ and JuhÃ¡sz, LÃ¡szlÃ³ and Batta, Gyula and BorbÃ¡s, AnikÃ³ and SomsÃ¡k, LÃ¡szlÃ³ (2017) Unprecedented b-manno type thiodisaccharides with a C-glycosylic function by photoinitiated hydrothiolation of 1-C-substituted glycals. New Journal of Chemistry, 41 (3). pp. 1284-1292. ISSN 1144-0546, ESSN: 1369-9261
Kapcsolat:	http://real.mtak.hu/63473/ https://doi.org/10.1039/c6nj03751h DOI: 10.1039/C6NJ03751H