NDA
Bejelentkezés
Kapcsolat
Time-kill study and synergistic activity of cell-wall inhibitor antibiotics in combination with gentamicin against Enterococcus faecalis and Enterococcus faecium |
Tartalom: | http://real.mtak.hu/62903/ |
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Archívum: | MTA Könyvtár |
Gyűjtemény: |
Status = Published
Type = Article |
Cím: |
Time-kill study and synergistic activity of cell-wall inhibitor antibiotics in combination with gentamicin against Enterococcus faecalis and Enterococcus faecium
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Létrehozó: |
Aligholi, Marzieh
Emaneini, Mohammad
Taherikalani, Morovat
Shahsavan, Shadi
Jabalameli, Fereshteh
Asadollahi, Parisa
Khoramian, Babak
Eslampour, Mohammad Amin
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Kiadó: |
Akadémiai Kiadó
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Dátum: |
2011
info:eu-repo/date/embargoEnd/2031-09-30
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Téma: |
QR Microbiology / mikrobiolĂłgia
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Tartalmi leírás: |
The synergy between gentamicin and vancomycin, teicoplanin, ampicillin and linezolid was studied by time-kill method. Two clinical vancomycin resistant enterococci (VRE) and two vancomycin susceptible enterococci (VSE) isolates were used. Different concentrations of antibiotics were combined. Two VSE strains and the control strain exhibited synergism with the combination of gentamicin, vancomycin, teicoplanin, ampicillin and linezolid. Two VRE strains exhibited synergism with the combination of gentamicin and ampicillin. Synergy between gentamicin and vancomycin, teicoplanin and linezolid was not observed against these isolates. The VRE isolates were positive for vanA, aac (6′)-Ie aph (2“) and aph (3′)-IIIa genes and their vancomycin, teicoplanin and gentamicin MICs were 512 μg/ml, 512 μg/ml and >4000 μg/ml, respectively. In order to treat serious enterococcal infections, further clinical evaluation is needed to examine the in vitro combined effects of gentamicin and vancomycin, teicoplanin and linezolid.
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Nyelv: |
magyar
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Típus: |
Article
PeerReviewed
info:eu-repo/semantics/article
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Formátum: |
text
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Azonosító: |
Aligholi, Marzieh and Emaneini, Mohammad and Taherikalani, Morovat and Shahsavan, Shadi and Jabalameli, Fereshteh and Asadollahi, Parisa and Khoramian, Babak and Eslampour, Mohammad Amin (2011) Time-kill study and synergistic activity of cell-wall inhibitor antibiotics in combination with gentamicin against Enterococcus faecalis and Enterococcus faecium. Acta Microbiologica et Immunologica Hungarica, 58 (3). pp. 219-226. ISSN 1217-8950
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Kapcsolat: |
https://doi.org/10.1556/AMicr.58.2011.3.5
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Létrehozó: |
info:eu-repo/semantics/embargoedAccess
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