Characterisation of the first VIM metallo- β -lactamase-producing Pseudomonas aeruginosa clinical isolate in Serbia
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Tartalom: http://real.mtak.hu/62657/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published

Type = Article
Cím:
Characterisation of the first VIM metallo- β -lactamase-producing Pseudomonas aeruginosa clinical isolate in Serbia
Létrehozó:
Lepsanovic, Zorica
Libisch, B.
Tomanovic, Branka
Nonkovic, Zorka
Balogh, Boglárka
FĂĽzi, M.
Kiadó:
Akadémiai Kiadó
Dátum:
2008
info:eu-repo/date/embargoEnd/2028-12-31
Téma:
QR Microbiology / mikrobiolĂłgia
Tartalmi leírás:
From the Central-East European region the first VIM metallo-
β
-lactamase (MBL) producing
Pseudomonas aeruginosa
strains were published from Croatia, Poland and Hungary. The aim of this study was to assess the contribution of MBL-production to carbapenem-resistance among
P. aeruginosa
clinical isolates in the Military Medical Academy (MMA) in Belgrade, Serbia between August 2004 and September 2007. Only one
P. aeruginosa
isolate with strain number 722 proved MBL-positive that harboured a novel class 1 integron with a
blaVIM-2-like cassette in the first position, followed by
orfD
, a putative gene with unknown function. Our data indicate that MBL-producing strains occur at a prevalence of less than 1% among imipenemnonsusceptible
P. aeruginosa
clinical isolates in this Belgrade hospital. The newly identified VIM MBL-producing
P. aeruginosa
strain 722 could be assigned to serotype O11, and it was panresistant to all antimicrobials tested. The isolate displayed sequence type ST235 by multilocus sequence typing which is the founder sequence type of the previously identified international clonal complex CC11 that already contains
blaVIM-positive isolates from Italy, Greece, Sweden, Hungary and Poland. In conclusion, this is the first report of VIM MBL-producing
P. aeruginosa
from Serbia and also of the occurrence of such isolates belonging to the international clonal complex CC11 in this country.
Nyelv:
magyar
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Lepsanovic, Zorica and Libisch, B. and Tomanovic, Branka and Nonkovic, Zorka and Balogh, Boglárka and Füzi, M. (2008) Characterisation of the first VIM metallo- β -lactamase-producing Pseudomonas aeruginosa clinical isolate in Serbia. Acta Microbiologica et Immunologica Hungarica, 55 (4). pp. 447-454. ISSN 1217-8950
Kapcsolat:
https://doi.org/10.1556/AMicr.55.2008.4.9
Létrehozó:
info:eu-repo/semantics/embargoedAccess