NDA
Bejelentkezés
Kapcsolat
Adventures with ABC-proteins: Highly Conserved ATP-dependent Transporters |
Tartalom: | http://real.mtak.hu/62284/ |
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Archívum: | MTA Könyvtár |
Gyűjtemény: |
Status = Published
Type = Article |
Cím: |
Adventures with ABC-proteins: Highly Conserved ATP-dependent Transporters
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Létrehozó: |
Holland, Katalin A.
Holland, I. Barry
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Kiadó: |
Akadémiai Kiadó
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Dátum: |
2005
info:eu-repo/date/embargoEnd/2025-10-31
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Téma: |
QR Microbiology / mikrobiolĂłgia
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Tartalmi leírás: |
The general properties of ABC transporters, from bacteria to humans, including a brief history of their initial discovery, are considered. ABC transporters, one of the largest protein super families and vital for human health, are in toto responsible for the transport of an enormous range of molecules from ions (CFTR) or anti-tumour drugs (Pgp/MDR) to large polypeptides. Nevertheless, all ABC transporters are powered by a conserved ATPase the ABC or NBD domain, using in all probability the same basic mechanism of action for the hydrolysis of ATP and its coupling to the transport process. Based on recent high resolution structures of several NBDs and an intact transporter, a model of how dimers of these important proteins function will be discussed, with particular attention to HlyB, the ABC transporter from E. coli.
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Nyelv: |
magyar
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Típus: |
Article
PeerReviewed
info:eu-repo/semantics/article
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Formátum: |
text
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Azonosító: |
Holland, Katalin A. and Holland, I. Barry (2005) Adventures with ABC-proteins: Highly Conserved ATP-dependent Transporters. Acta Microbiologica et Immunologica Hungarica, 52 (3-4). pp. 309-322. ISSN 1217-8950
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Kapcsolat: |
https://doi.org/10.1556/AMicr.52.2005.3-4.4
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Létrehozó: |
info:eu-repo/semantics/embargoedAccess
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