A mitochondrial-derived vesicle HOPS to endolysosomes using Syntaxin-17.
Létrehozó:
Juhász, Gábor
Kiadó:
Rockefeller University Press
Dátum:
2016
Téma:
QH301 Biology / biolĂłgia
Tartalmi leírás:
Damaged mitochondrial content is packaged in mitochondrial-derived vesicles (MDVs), which are targeted for degradation through an unclear mechanism. McLelland et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603105) show that the SNARE Syntaxin-17 mediates MDV fusion with endolysosomes, promoting the delivery of mitochondrial cargo to lysosomes for degradation.
Juhász, Gábor (2016) A mitochondrial-derived vesicle HOPS to endolysosomes using Syntaxin-17. JOURNAL OF CELL BIOLOGY, 214 (3). pp. 241-243. ISSN 0021-9525
