NDA@SZTAKI

Interactions at the Peptide/Silicon Surfaces: Evidence of Peptide Multilayer Assembly

Pápa, Zsuzsanna

Ramakrishnan, Sathish Kumar

Martin, Marta

Cloitre, Thierry

Zimányi, László

Budai, Judit

TĂłth, Zsolt

Gergely, Csilla

American Chemical Society

2016

QD Chemistry / kémia

QH3020 Biophysics / biofizika

Selective deposition of peptides from liquid solutions to n- and p-doped silicon has been demonstrated. The selectivity is governed by peptide/silicon adhesion differences. A non-invasive, fast characterization of the obtained peptide layers is required to promote their application for interfacing silicon-based devices with biological material. In this study we show that spectroscopic ellipsometry - a method increasingly used for the investigation of bio-interfaces - can provide essential information about the amount of adsorbed peptide material and the degree of coverage on silicon surfaces. We observed the formation of peptide multilayers for a strongly binding adhesion peptide on p-doped silicon. Application of the patterned layer ellipsometric evaluation method combined with Sellmeier-dispersion led to physically consistent results, which describe well the optical properties of peptide layers in the visible spectral range. This evaluation allowed the estimation of surface coverage, which is an important indicator of adsorption quality. The ellipsometric findings were well supported by atomic force microscopy results.

angol

Article

PeerReviewed

info:eu-repo/semantics/article

text

http://real.mtak.hu/47344/1/PapaLangmuirManu.pdf

Pápa, Zsuzsanna and Ramakrishnan, Sathish Kumar and Martin, Marta and Cloitre, Thierry and Zimányi, László and Budai, Judit and Tóth, Zsolt and Gergely, Csilla (2016) Interactions at the Peptide/Silicon Surfaces: Evidence of Peptide Multilayer Assembly. LANGMUIR, 32 (28). pp. 7250-7258. ISSN 0743-7463

http://real.mtak.hu/47344/

http://dx.doi.org/10.1021/acs.langmuir.6b00916

MTMT:3090787; doi:10.1021/acs.langmuir.6b00916