| Tartalom: |
http://real.mtak.hu/47320/ |
| Archívum: |
MTA Könyvtár |
| Gyűjtemény: |
Status = Published
Type = Article
|
| Cím: |
Regulation of B cell functions by Toll-like receptors and complement
|
| Létrehozó: |
Kremlitzka, Mariann
Mácsik-Valent, Bernadett
Erdei, Anna
|
| Kiadó: |
Elsevier; North-Holland
|
| Dátum: |
2016
|
| Téma: |
QR180 Immunology / immunolĂłgia
|
| Tartalmi leírás: |
Abstract B cell functions triggered by the clonally-rearranged antigen-specific B cell receptor (BCR) are regulated by several germ-line encoded receptors – including Toll-like receptors (TLRs) and complement receptors (CRs). Simultaneous or sequential engagement of these structures expressed either on the cell membrane or intracellularly, may fundamentally alter and fine tune activation, antibody and cytokine production of B cells. Here we review the expression and function of TLRs and various C3 fragment binding CRs on B cells, emphasizing their role in different human B cell subsets under physiological and pathological conditions. Studies underlining the importance of the crosstalk between TLRs and CRs in regulating B cell functions are also highlighted.
|
| Nyelv: |
angol
|
| Típus: |
Article
PeerReviewed
info:eu-repo/semantics/article
|
| Formátum: |
text
|
| Azonosító: |
Kremlitzka, Mariann and Mácsik-Valent, Bernadett and Erdei, Anna (2016) Regulation of B cell functions by Toll-like receptors and complement. IMMUNOLOGY LETTERS, 178. pp. 37-44. ISSN 0165-2478
|
| Kapcsolat: |
MTMT:3098842; doi:10.1016/j.imlet.2016.07.015
|
