Xanthines Studied via Femtosecond Fluorescence Spectroscopy
  • Metaadatok
Tartalom: http://real.mtak.hu/46206/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published


Type = Article
Cím:
Xanthines Studied via Femtosecond Fluorescence Spectroscopy
Létrehozó:
Changenet-Barret, Pascale
KovĂĄcs, Lajos
Markovitsi, Dimitra
Gustavsson, Thomas
Kiadó:
MDPI
Dátum:
2016
Téma:
QD Chemistry / kĂŠmia
QH3011 Biochemistry / biokĂŠmia
Tartalmi leírás:
Xanthines represent a wide class of compounds closely related to the DNA bases adenine and guanine. Ubiquitous in the human body, they are capable of replacing natural bases in double helices and give rise to four-stranded structures. Although the use of their fluorescence for analytical purposes was proposed, their fluorescence properties have not been properly characterized so far. The present paper reports the first fluorescence study of xanthine solutions relying on femtosecond spectroscopy. Initially, we focus on 3-methylxanthine, showing that this compound exhibits non-exponential fluorescence decays with no significant dependence on the emission wavelength. The fluorescence quantum yield (3 × 10−4) and average decay time (0.9 ps) are slightly larger than those found for the DNA bases. Subsequently, we compare the dynamical fluorescence properties of seven mono-, di- and trimethylated derivatives. Both the fluorescence decays and fluorescence anisotropies vary only weakly with the site and the degree of methylation. These findings are in line with theoretical predictions suggesting the involvement of several conical intersections in the relaxation of the lowest singlet excited state.
Nyelv:
angol
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Changenet-Barret, Pascale and KovĂĄcs, Lajos and Markovitsi, Dimitra and Gustavsson, Thomas (2016) Xanthines Studied via Femtosecond Fluorescence Spectroscopy. MOLECULES, 21 (12). pp. 1-11. ISSN 1420-3049
Kapcsolat:
MTMT:3147883; doi:10.3390/molecules21121668