| Tartalom: |
http://real.mtak.hu/41945/ |
| Archívum: |
MTA Könyvtár |
| Gyűjtemény: |
Status = Published
Type = Article
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| Cím: |
Amino acid recognition by fine tuning the association constants: Tailored naphthalimides in pillar[5]arene-based indicator displacement assays
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| Létrehozó: |
BojtĂĄr, MĂĄrton GĂĄspĂĄr
Paudics, Adrien
Hessz, DĂłra
Kubinyi, MiklĂłs
Bitter, IstvĂĄn
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| Kiadó: |
Royal Society of Chemistry
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| Dátum: |
2016-09-05
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| Téma: |
QD Chemistry / kĂŠmia
QD02 Physical chemistry / fizikai kĂŠmia
QD04 Organic chemistry / szerves kĂŠmia
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| Tartalmi leírás: |
Three aminonaphthalimide derivatives were synthesized bearing different anchoring groups in their 4-position in order to adjust the supramolecular interactions with carboxylato-pillar[5]arene (WP5), an anionic, water-soluble host. The modification of the anchor groups resulted in varying association constants embracing three orders of magnitude (Ka from âź103 to âź106) in buffered water. Since the fluorophore responded significantly to the electronic environment, large fluorescence quenching was observed with the anionic WP5 host. The naphthalimide indicator-WP5 supramolecular assemblies were used to detect arginine and lysine with complete selectivity over other non-basic Îą-amino acids by turn-on fluorescence. The same assemblies proved to be highly sensitive fluorescence displacement assays for the detection of cadaverine
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| Nyelv: |
magyar
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| Típus: |
Article
PeerReviewed
info:eu-repo/semantics/article
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| Formátum: |
text
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| Azonosító: |
BojtĂĄr, MĂĄrton GĂĄspĂĄr and Paudics, Adrien and Hessz, DĂłra and Kubinyi, MiklĂłs and Bitter, IstvĂĄn (2016) Amino acid recognition by fine tuning the association constants: Tailored naphthalimides in pillar[5]arene-based indicator displacement assays. RSC Advances, 6. pp. 86269-86275. ISSN 2046-2069
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