Rabbits in Mycotoxin Research at Kaposvár University
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Tartalom: http://real.mtak.hu/40148/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published

Type = Conference or Workshop Item
Cím:
Rabbits in Mycotoxin Research at Kaposvár University
Létrehozó:
Kachlek, Mariam Lilia
SzabĂł-Fodor, Judit
Kovács, Melinda
Dátum:
2016-05-25
Téma:
SF Animal culture / állattenyésztés
Tartalmi leírás:
In toxicity testing a lot of animals have been used as models with rodents being the most frequently used due to
their small size and inexpensive purchase. Rabbits are large enough to permit easy handling and at the same time
to facilitate easy blood and semen collection as well as other more intrusive practices like embryo transfer. Thus
rabbits have been used in many studies on developmental and reproductive toxicity. Mycotoxin research is another field in which rabbits have been the animal of choice. Mycotoxins are the secondary metabolites of fungi which can cause a series of syndromes and health implications to both animals and humans. Rabbits are highly susceptible to aflatoxin B1 (AFB1). Ochratoxin A (OTA) can exert teratogenic effects whereas fumonisins can cause renal or liver toxicity to rabbits. In Kaposvár University both single (FB1, T-2, DON) and combined (FB1+T-2, DON+ZEA and FB1+DON+ZEA) experiments have been conducted. T-2 is the most studied mycotoxin and the No observed Adverse Effect Level (NOAEL) has been determined in rabbit bucks. The effect of FB1 has also been studied confirming the renal toxicity in pregnant rabbit does and the foetuses. ZEA has also been studied in combination with only DON or FB1 and DON. The effect of DON in concentration twice as much as the guidance value set by the European Commision for complementary and complete feedstuffs; rabbits were not severely affected. The two targets were the liver (altered morphology) and the immune system with no negative secondary effect.
Nyelv:
magyar
Típus:
Conference or Workshop Item
PeerReviewed
info:eu-repo/semantics/conferenceObject
Formátum:
text
Azonosító:
Kachlek, Mariam Lilia and Szabó-Fodor, Judit and Kovács, Melinda (2016) Rabbits in Mycotoxin Research at Kaposvár University. In: 28. Nyúltenyésztési Tudományos Nap, 2016.05.25, Kaposvár.
Kapcsolat: