ACE and ACTN3 genes polymorphisms among female Hungarian athletes in the aspect of sport disciplines
  • Metaadatok
Tartalom: http://real.mtak.hu/38135/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published

Type = Article
Cím:
ACE and ACTN3 genes polymorphisms among female Hungarian athletes in the aspect of sport disciplines
Létrehozó:
Bosnyák, E
Trájer, E
Udvardy, A
Komka, Z
Protzner, A
Kováts, T
Györe, I
TĂłth, M
Pucsok, J
Szmodis, M
Kiadó:
Akadémiai Kiadó
Dátum:
2015
Téma:
R1 Medicine (General) / orvostudomány általában
Tartalmi leírás:
The aim of the study was to determine the importance of two sport-associated gene polymorphisms, alpha-actinin-3 R577X (ACTN3) and angiotensin-converting enzyme I/D (ACE), among Hungarian athletes in different sports. The examination was carried out only on women (n = 100). Sport-specific groups were formed in order to guarantee the most homogeneous clusters. Human genomic DNA was isolated from blood, and genotyping was performed by polymerase chain reaction. To measure the differences between the participating groups, Chi-squared test was performed using Statistica 9.0 for Windows® (significance level: p < 0.05). In comparing the ACE I/D allele frequencies, significant difference was detected between water polo (I = 61.11%; D = 38.89%) and combat sports (I = 35.71%, D = 64.29%) athletes (p < 0.03). There was no statistical difference when ACE I/D alleles in combat sports and kayaking/rowing (p > 0.05) were compared. A similarity was detectable in the I allele frequencies of the water polo (61.11%) and kayaking/rowing (56.67%) groups. The ACTN3 R/X polymorphism showed no differences in comparison with the sport groups. R allele frequencies were higher in every group compared to the X allele. The potential significance of the ACE I allele in sports of an aerobic nature was not clearly confirmed among Hungarian athletes.
Nyelv:
magyar
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Bosnyák, E and Trájer, E and Udvardy, A and Komka, Z and Protzner, A and Kováts, T and Györe, I and Tóth, M and Pucsok, J and Szmodis, M (2015) ACE and ACTN3 genes polymorphisms among female Hungarian athletes in the aspect of sport disciplines. Acta Physiologica Hungarica, 102 (4). pp. 451-458. ISSN 0231-424X
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