| Tartalom: |
http://real.mtak.hu/36367/ |
| Archívum: |
MTA Könyvtár |
| Gyűjtemény: |
Status = Published
Type = Article
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| Cím: |
Intrinsically disordered proteins: Emerging interaction specialists
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| Létrehozó: |
Tompa, PĂŠter
SchĂĄd, Ăva
Tantos, Ăgnes
KalmĂĄr, Lajos
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| Kiadó: |
Elsevier
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| Dátum: |
2015
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| Téma: |
QH3015 Molecular biology / molekulĂĄris biolĂłgia
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| Tartalmi leírás: |
Intrinsically disordered proteins or regions of proteins (IDPs/IDRs) most often function through protein-protein interactions, when they permanently or transiently bind partner molecules with diverse functional consequences. There is a rapid advance in our understanding of the ensuing functional modes, obtained from describing atomic details of individual complexes, proteome-wide studies of interactomes and characterizing loosely assembled hydrogels and tightly packed amyloids. Here we briefly survey the most important recent methodological developments and structural-functional observations, with the aim of increasing the general appreciation of IDPs/IDRs as 'interaction specialists'. Š 2015 Elsevier Ltd.
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| Nyelv: |
angol
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| Típus: |
Article
PeerReviewed
info:eu-repo/semantics/article
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| Formátum: |
text
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| Azonosító: |
Tompa, PĂŠter and SchĂĄd, Ăva and Tantos, Ăgnes and KalmĂĄr, Lajos (2015) Intrinsically disordered proteins: Emerging interaction specialists. CURRENT OPINION IN STRUCTURAL BIOLOGY, 35. pp. 49-59. ISSN 0959-440X
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| Kapcsolat: |
MTMT:2951720; doi:10.1016/j.sbi.2015.08.009
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