Activity/inactivity circadian rhythm shows high similarities between young obesity-induced rats and old rats
  • Metaadatok
Tartalom: http://real.mtak.hu/35681/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published

Type = Article
Cím:
Activity/inactivity circadian rhythm shows high similarities between young obesity-induced rats and old rats
Létrehozó:
Bravo Santos, R
Delgado, J
Cubero, J
Franco, L
Ruiz-Moyano, S
Mesa, M
RodrĂ­guez, AB
Uguz, C
Barriga, C
Kiadó:
Akadémiai Kiadó
Dátum:
2016
Téma:
R1 Medicine (General) / orvostudomány általában
Tartalmi leírás:
The objective of the present study was to compare differences between elderly rats and young obesity-induced rats in their activity/inactivity circadian rhythm. The investigation was motivated by the differences reported previously for the circadian rhythms of both obese and elderly humans (and other animals), and those of healthy, young or mature individuals. Three groups of rats were formed: a young control group which was fed a standard chow for rodents; a young obesity-induced group which was fed a high-fat diet for four months; and an elderly control group with rats aged 2.5 years that was fed a standard chow for rodents. Activity/inactivity data were registered through actimetry using infrared actimeter systems in each cage to detect activity. Data were logged on a computer and chronobiological analysis were performed. The results showed diurnal activity (sleep time), nocturnal activity (awake time), amplitude, acrophase, and interdaily stability to be similar between the young obesity-induced group and the elderly control group, but different in the young control group. We have concluded that obesity leads to a chronodisruption status in the body similar to the circadian rhythm degradation observed in the elderly.
Nyelv:
angol
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Bravo Santos, R and Delgado, J and Cubero, J and Franco, L and Ruiz-Moyano, S and Mesa, M and RodrĂ­guez, AB and Uguz, C and Barriga, C (2016) Activity/inactivity circadian rhythm shows high similarities between young obesity-induced rats and old rats. Physiology International, 103 (1). pp. 65-74. ISSN 2498-602X
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