Age-related presence of selected viral and bacterial pathogens in paraffin-embedded lung samples of dogs with pneumonia
  • Metaadatok
Tartalom: http://real.mtak.hu/35569/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published
Type = Article
Cím:
Age-related presence of selected viral and bacterial pathogens in paraffin-embedded lung samples of dogs with pneumonia
Létrehozó:
Wöhrer, Daniela
Spergser, Joachim
Bagrinovschi, Gabriela
Möstl, Karin
Weissenböck, Herbert
Kiadó:
Akadémiai Kiadó
Dátum:
2016
Téma:
SV Veterinary science / állatorvostudomány
Tartalmi leírás:
The aim of this retrospective study was to detect selected pathogens in pneumonic lung tissue of dogs of different age groups by immunohistochemistry (IHC), in situ hybridisation (ISH) or polymerase chain reaction (PCR) in order to get information about their involvement in pneumonia formation. In archived formalin-fixed and paraffin wax-embedded lung samples from 68 cases with the clinical and histologic diagnosis of pneumonia the histological pattern of pneumonia was re-evaluated and the samples were further investigated for the following infectious agents: canine distemper virus (CDV), canine adenovirus type 2 (CAV-2), canine respiratory coronavirus (CRCoV), Bordetella (B.) bronchiseptica, Pasteurella (P.) multocida, Mycoplasma spp., and Pneumocystis spp. In 47.1% of the samples at least one of the featured respiratory pathogens was detected. In 31.3% of these positive samples more than one pathogen could be found. The correct detection of CDV had been achieved in ten out of eleven positive cases (90.9%) upon initial investigation, but the presence of bacterial pathogens, like B. bronchiseptica (10 cases) and P. multocida (17 cases) had been missed in all but one case. While CDV and CRCoV infections were exclusively found in dogs younger than one year, the vast majority of infections with P. multocida and B. bronchiseptica were both common either in dogs younger than 4 months or older than one year. Thus, this retrospective approach yielded valuable data on the presence, absence and prevalence of certain respiratory pathogens in dogs with pneumonia.
Nyelv:
angol
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Wöhrer, Daniela and Spergser, Joachim and Bagrinovschi, Gabriela and Möstl, Karin and Weissenböck, Herbert (2016) Age-related presence of selected viral and bacterial pathogens in paraffin-embedded lung samples of dogs with pneumonia. Acta Veterinaria Hungarica, 64 (1). pp. 103-115. ISSN 0236-6290
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