Short-term effects of T-2 toxin exposure on some lipid peroxide and glutathione redox parameters of broiler chickens
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Tartalom: http://real.mtak.hu/35235/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published

Type = Article
Cím:
Short-term effects of T-2 toxin exposure on some lipid peroxide and glutathione redox parameters of broiler chickens
Létrehozó:
BĂłcsai, Andrea
Pelyhe, Csilla
Zándoki, Erika
Ancsin, Zsolt
SzabĂł-Fodor, Judit
Erdélyi, Márta
MĂ©zes, MiklĂłs
Balogh, Krisztián
Kiadó:
Wiley
Dátum:
2016
Téma:
SF Animal culture / állattenyésztés
Tartalmi leírás:
The purpose of this study was to investigate the short-term effects of T-2 toxin exposure (3.09 mg/kg feed) on
lipid peroxidation and glutathione redox system of broiler chicken. A total of 54 Cobb 500 cockerels were randomly
distributed to two experimental groups at 21 days of age. Samples (blood plasma, red blood cell, liver, kidney
and spleen) were collected every 12 h during a 48-h period. The results showed that the initial phase of lipid
peroxidation, as measured by conjugated dienes and trienes in the liver, was continuously, but not significantly
higher in T-2 toxin-dosed birds than in control birds. The termination phase of lipid peroxidation, as measured
by malondialdehyde, was significantly higher in liver and kidney as a result of T-2 toxin exposure at the end of
the experimental period (48th hour). The glutathione redox system activated shortly after starting the T-2 toxin
exposure, which is supported by the significantly higher concentration of reduced glutathione and glutathione
peroxidase activity in blood plasma at 24 and 48 h, in liver at 12, 24 and 36 h, and in kidney and spleen at 24 h.
These results suggest that T-2 toxin, or its metabolites, may be involved in the generation of reactive oxygen substances
which causes an increase in lipid peroxidation, and consequently activates the glutathione redox system,
namely synthesis of reduced glutathione and glutathione peroxidase.
Nyelv:
magyar
Típus:
Article
PeerReviewed
info:eu-repo/semantics/article
Formátum:
text
Azonosító:
Bócsai, Andrea and Pelyhe, Csilla and Zándoki, Erika and Ancsin, Zsolt and Szabó-Fodor, Judit and Erdélyi, Márta and Mézes, Miklós and Balogh, Krisztián (2016) Short-term effects of T-2 toxin exposure on some lipid peroxide and glutathione redox parameters of broiler chickens. Journal of Animal Physiology and Animal Nutrition, 100 (3). pp. 520-525. ISSN 0931-2439, ESSN: 1439-0396
Kapcsolat:
DOI: 10.1111/jpn.12399