NDA@SZTAKI

Integrated circoviral rep-like sequences in the genome of cyprinid fish

Fehér, Enikő

Székely, Csaba

Lőrincz, Márta

Cech, Gábor

Tuboly, Tamás

Bányai, Krisztián

Farkas, Szilvia

Springer Verlag (Germany)

2013

QL Zoology / állattan

QR355 Virology / víruskutatás

Recently a new group of circoviruses have been
detected in tissues of Barbel fish and European catfish in
Hungary. In our study circovirus genomes were screened in
eight additional fish species for the detection and characterization
of circoviruses. Two species of these bore circoviral
sequences based on conventional PCR assay
targeting the replication-associated protein coding gene
fragments. Interestingly, the methods successfully used
before failed to amplify other parts of the circular viral
genome, suggesting the presence of partial, integrated
genetic elements in the genome of the host. The successfully
sequenced fragments of the Indian rohu (Labeo rohita)
encoded mutations which may cause frameshifts or
termination in the coding region described previously in
other vertebrates. Phylogenetic analyses presumed that
integration of the viral genetic elements might have progressed
concurrently or following the diversification of
cyprinid fish. Further studies on the nature of whole circovirus genomes and integrated elements may help to
understand their potential role and evolution in different
fish species.

angol

Article

PeerReviewed

info:eu-repo/semantics/article

text

http://real.mtak.hu/9675/1/2013_VirGen_circo-rep.pdf

Fehér, Enikő and Székely, Csaba and Lőrincz, Márta and Cech, Gábor and Tuboly, Tamás and Bányai, Krisztián and Farkas, Szilvia (2013) Integrated circoviral rep-like sequences in the genome of cyprinid fish. VIRUS GENES, 47. pp. 374-377. ISSN 0920-8569

http://real.mtak.hu/9675/

MTMT:2332399; doi:10.1007/s11262-013-0928-9

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