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Imaging method for model-based control of tumor diseases

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Tartalom: http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumbe...
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published

Type = Book Section
Cím:
Imaging method for model-based control of tumor diseases
Létrehozó:
Kiss, Bálint
Sápi, Johanna
Kovács, Levente
Közreműködő:
Szakál, Anikó
Dátum:
2013
Téma:
R1 Medicine (General) / orvostudomány általában
Tartalmi leírás:
Modern approaches of cancer therapies have specific effect on the typical mechanisms of uncontrollably growing and multiplying tumor cells. These targeted therapies can be more efficient than commonly applied methods in clinical practice. Antiangiogenic therapy prevents tumors from forming new blood vessels to ensure sufficient oxygen and nutrients. Without appropriate vascularization, the development of the tumor is inhibited, thus metastasis formation is blocked. In this paper we briefly review the importance of antiangiogenic therapy. To improve mathematical models of tumor growth under angiogenic inhibitors, the process of tumor development must be analyzed. We have chosen Magnetic Resonance Imaging (MRI) to follow up the dynamics of tumor growth and monitor the effect of angiogenic inhibitors. T1-weighted images have been acquired using gradient-echo, spin echo and fast spin echo sequences to examine subcutaneous mouse tumors. We have found that fast spin echo results the best solution: short data acquisition time and good contrast without contrast agent.
Típus:
Book Section
NonPeerReviewed
Formátum:
text
Azonosító:
Kiss, Bálint and Sápi, Johanna and Kovács, Levente (2013) Imaging method for model-based control of tumor diseases. In: SISY 2013. IEEE Hungary Section, Budapest, pp. 271-275. ISBN 978-1-4799-0303-0
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