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An insight into the synthesis of novel arylsubstituted alicyclic b-amino acid derivatives through substrate-directed palladium-catalysed regio- and stereoselective cross-coupling |
| Tartalom: | http://real.mtak.hu/26342/ |
|---|---|
| Archívum: | MTA Könyvtár |
| Gyűjtemény: |
Status = Published
Type = Article |
| Cím: |
An insight into the synthesis of novel arylsubstituted
alicyclic b-amino acid derivatives
through substrate-directed palladium-catalysed
regio- and stereoselective cross-coupling
|
| Létrehozó: |
Nonn, Melinda
Kiss, Loránd
Hanninen, Mikko
Fülöp, Ferenc
|
| Dátum: |
2015
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| Téma: |
QD Chemistry / kémia
QD04 Organic chemistry / szerves kémia
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| Tartalmi leírás: |
Novel aryl-substituted alicyclic b-amino acid derivatives were synthesized through substrate-determined
palladium-catalysed cross-coupling of aryl iodides with five- or six-membered cycloalkene b-amino esters. The arylations were investigated with different catalysts, solvents, bases and aryl halides, and with some cyclohexene 2-aminocarboxylate isomers. The stereochemistry and the position of the ring olefinic bond of the starting 2-aminocycloalkanecarboxylate influenced the coupling reaction, and predetermined the structure of the arylated product. |
| Típus: |
Article
PeerReviewed
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| Formátum: |
text
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| Azonosító: |
Nonn, Melinda and Kiss, Loránd and Hanninen, Mikko and Fülöp, Ferenc (2015) An insight into the synthesis of novel arylsubstituted alicyclic b-amino acid derivatives through substrate-directed palladium-catalysed regio- and stereoselective cross-coupling. RSC Advances, 5. pp. 13628-13634.
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| Kapcsolat: |
