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An insight into the synthesis of novel arylsubstituted alicyclic b-amino acid derivatives through substrate-directed palladium-catalysed regio- and stereoselective cross-coupling

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Tartalom: http://real.mtak.hu/26342/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published


Type = Article
Cím:
An insight into the synthesis of novel arylsubstituted alicyclic b-amino acid derivatives through substrate-directed palladium-catalysed regio- and stereoselective cross-coupling
Létrehozó:
Nonn, Melinda
Kiss, Loránd
Hanninen, Mikko
Fülöp, Ferenc
Dátum:
2015
Téma:
QD Chemistry / kémia
QD04 Organic chemistry / szerves kémia
Tartalmi leírás:
Novel aryl-substituted alicyclic b-amino acid derivatives were synthesized through substrate-determined
palladium-catalysed cross-coupling of aryl iodides with five- or six-membered cycloalkene b-amino
esters. The arylations were investigated with different catalysts, solvents, bases and aryl halides, and with
some cyclohexene 2-aminocarboxylate isomers. The stereochemistry and the position of the ring
olefinic bond of the starting 2-aminocycloalkanecarboxylate influenced the coupling reaction, and
predetermined the structure of the arylated product.
Típus:
Article
PeerReviewed
Formátum:
text
Azonosító:
Nonn, Melinda and Kiss, Loránd and Hanninen, Mikko and Fülöp, Ferenc (2015) An insight into the synthesis of novel arylsubstituted alicyclic b-amino acid derivatives through substrate-directed palladium-catalysed regio- and stereoselective cross-coupling. RSC Advances, 5. pp. 13628-13634.
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