Chronic infections and histamine, CRP and IL-6 levels after percutaneous transluminal coronary angioplasty
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Tartalom: http://real.mtak.hu/5848/
Archívum: MTA Könyvtár
Gyűjtemény: Status = Published


Type = Article
Cím:
Chronic infections and histamine, CRP and IL-6 levels after percutaneous transluminal coronary angioplasty
Létrehozó:
Petrovay, F.
Heltai, Krisztina
Kis, Z.
Tresó, Bálint
Gönczöl, Éva
Burián, Katalin
Endrész, Valéria
Vályi-Nagy, István
Kiadó:
Birkhauser Verlag
Dátum:
2007
Téma:
QR Microbiology / mikrobiológia
RZ Other systems of medicine / orvostudomány egyéb területei
Tartalmi leírás:
Objective and design: Our hypothesis was that
percutaneous transluminal coronary angioplasty (PTCA) reactivates
certain pathogens that contribute to infl ammatory
processes after the intervention.
Subjects: We determined the levels of antibodies to human
Hsp60 and levels of histamine, CRP and IL-6 in sera from
28 patients of unstable angina prior to and on days 4 and 14
after PTCA. We compared the presence of Chlamydophila
pneumoniae (Cpn) and human cytomegalovirus (HCMV)
DNA in peripheral blood, and levels of antibodies to Cpn,
HCMV, herpes simplex virus, Epstein-Barr virus and mycobacterial
Hsp65 in the serum.
Results: Higher prevalence of Cpn and HCMV DNA was
demonstrated after PTCA than before, but titers of antibodies
to the pathogens did not increase. Levels of histamine,
CRP and IL-6 were enhanced after PTCA. There was no association
between the levels of histamine, CRP and IL-6 and
the rate of pathogen DNA, or antibody titers to the pathogens,
except an association between Cpn IgA and histamine
levels before PTCA.
Conclusions: Reactivation of Cpn and HCMV and infl ammatory
change characterized by increased levels of histamine,
CRP and IL-6 following PTCA are suggested. An association
might exist between Cpn IgA antibody and histamine
levels in patients of unstable angina.
Típus:
Article
PeerReviewed
Formátum:
text
Azonosító:
Petrovay, F. and Heltai, Krisztina and Kis, Z. and Tresó, Bálint and Gönczöl, Éva and Burián, Katalin and Endrész, Valéria and Vályi-Nagy, István (2007) Chronic infections and histamine, CRP and IL-6 levels after percutaneous transluminal coronary angioplasty. INFLAMMATION RESEARCH, 56 (9). pp. 362-367. ISSN 1023-3830
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