Ultraviolet light phototherapy for allergic rhinitis.
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Archívum: MTA Könyvtár
Gyűjtemény: Status = Published




Type = Article
Cím:
Ultraviolet light phototherapy for allergic rhinitis.
Létrehozó:
Kemény, Lajos
Koreck, A.
Kiadó:
Elsevier
Dátum:
2007
Téma:
QC Physics / fizika
QC02 Optics / fénytan
RF Otorhinolaryngology / orr-, fül-, gégészet
RZ Other systems of medicine / orvostudomány egyéb területei
Tartalmi leírás:
Phototherapy has a profound immunosuppressive effect and is widely used for the treatment of immune mediated skin diseases.
Phototherapy is able to inhibit immediate type hypersensitivity reaction in the skin. Intranasal phototherapy is a new approach for
treatment of allergic rhinitis. In two open studies, 308 nm excimer laser and topical PUVA therapy efficiently inhibited clinical
symptoms of allergic rhinitis. In a randomized, double-blind study combined low dose UVB, low dose UVA and visible light proved
to be effective in reducing symptom scores for sneezing, rhinorrhea, nasal itching and the total nasal score in ragweed allergic
patients. Mechanism of action of phototherapy is complex, it reduces the antigen presenting capacity of dendritic cells, induces
apoptosis of immune cells and inhibits synthesis and release of pro-inflammatory mediator from several cell types. Therefore, intranasal
phototherapy may represent an alternative treatment of allergic rhinitis and other inflammatory and immune mediated mucosal
diseases.
Típus:
Article
PeerReviewed
Formátum:
text
Azonosító:
Kemény, Lajos and Koreck, A. (2007) Ultraviolet light phototherapy for allergic rhinitis. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 87 (1). pp. 58-65. ISSN 1011-1344
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